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Gaia Medical Institute is a rapidly growing biotech company in La Jolla, CA. Our goal is to develop saliva biomarkers for noninvasive disease diagnostics. Our product pipeline includes saliva tests for Traumatic brain injury (TBI), Heart Failure, HIV/AIDS and Hydration monitoring. The Research Associate (RA) will serve as a research technician on the Digital Biomarker Assay team.
The RA will perform biomarker immunoassays of clinical saliva samples from patients with TBI and other diseases. The RA will perform multi-step biomarker assays that require advanced laboratory skills, understanding of protein chemistry and basic statistics. The RA must be able to work independently with a high level of self-initiative and accurate time management.
The RA will work under the direction of the Senior Research Associate and Lab Manager. The RA will be responsible for meticulous execution of the experimental work plans. This will include following Standard Operating Procedures in bench work, imaging and data analysis. The RA will also contribute to receiving and inventory of clinical samples, reagents and laboratory supplies, and the maintenance of laboratory equipment.
The ideal candidate will have a B.S. in molecular biology, biochemistry or related science, and a recent full time job experience of 2-3 years in a science laboratory.
MINIMUM QUALIFICATIONS
B.S. degree in molecular biology, biochemistry, chemistry or related science.
Full time laboratory position of 2-3 years.
Practical understanding of antibodies, recombinant proteins and immunoassays. Demonstrated hands-on experience with commercial antibodies and recombinant proteins.
Experience with basic laboratory techniques, equipment and software in molecular biology and biochemistry such as pipetting, pH measurement, centrifugation, SDS-PAGE electrophoresis, immunoblotting and digital microscopy.
Demonstrated ability to follow Standard Operation Procedures and Good Laboratory Practice procedures.
Demonstrated record of meticulously using a Laboratory Notebook.
Demonstrated computer skills for statistical data analysis. Ability to interpret and present data in the form of tables and charts.
Demonstrated knowledge and compliance with Environmental Health and Safety requirements for chemical waste disposal.
PREFERRED QUALIFICATIONS
Demonstrated experience in at least one of the following digital immunoassays:
o Immunohistochemistry (IHC): manual staining of tissue sections of cell smears using mouse and rabbit primary antibodies, biotinylated secondary antibodies, AP and HRP conjugates, colorimetric substrates, hematoxylin counterstain, robotic cover slipping, image capture using digital microscopy (Nikon or similar), scanning microscopy (Leica or similar) and digital image analysis (Visiopharm or similar).
o ECL Western blot using BioRad workflow with precast gels, Trans-Blot Turbo Transfer System, rabbit, mouse and goat primary antibodies, HRP conjugate chemiluminescent substrate and digital Chemidoc camera. Calculate molecular weight and protein concentration from digital Western blot data.
o Lateral-Flow Immunoassay (LFIA) using nitrocellulose test strip, gold or fluorescent label and digital reader.
Enthusiasm for learning and a genuine interest in scientific research is crucial to success in this job. Basic knowledge of biology and chemistry as typically attained by a Bachelor's degree.
Basic understanding of protein chemistry and proteomics.
We offer:
Competitive pay
Comprehensive training
Medical, Vision and Dental benefits
Paid time off and holidays
To apply:
Reply to this posting
Resume/CV
References (available upon request)
