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Apply NowApply LaterResearch Assistant IDepartment Description:The candidate will work in an established laboratory dedicated to understanding the molecular and genetic basis of ACTN4- related kidney disease. The laboratory utilizes a broad range of technologies, including human genetics technology, cellular assays, and working with mouse models. Primary responsibilities of this position include but are not limited to performing experiments using both novel and standard techniques, such as Western blotting, for molecular biology, cell culture and animal studies that characterize different kidney disease models. A successful candidate will have strong interest in learning and applying the techniques toward bettering understanding of kidney disease. Experience with whole animal work and iPS cell culture is highly valued. Candidates with degrees in Engineering and Physiology are also encouraged to apply.Job Location:Boston, MAReq ID:31416BRJob Summary:Under supervision of the principal investigator, conducts a variety of routine experiments using molecular, cell biology and/or biochemistry techniques. Records test results, calculates, transcribes, and analyzes data using basic statistics.The candidate will work in an established laboratory dedicated to understanding the molecular and genetic basis of ACTN4- related kidney disease. The laboratory utilizes a broad range of technologies, including human genetics technology, cellular assays, and working with mouse models. Primary responsibilities of this position include but are not limited to performing experiments using both novel and standard techniques for molecular biology, cell culture and animal studies that characterize different kidney disease models. A successful candidate will have strong interest in learning and applying the techniques toward bettering understanding of kidney disease. Experience with whole animal work and iPS cell culture is highly valued.Essential Responsibilities:
Conducts routine tests following established procedures, which may include assays, DNA sequencing, tissue culture, protein purification, Western blotting, PCR analysis, electrophoresis, chromatography.
Researches and collects basic study data through monitoring devices and maintains daily logs/basic records of methodologies and test results. With supervision, using databases, may summarize data and interpret results using descriptive statistics and basic hypothesis testing.
May write standard operating procedures for documentation and make informal presentations of these procedures to others in the lab.
Performs literature searches and library investigations as they relate to the research and/or as assigned.
Due to the dynamic environment in which research exists, must show flexibility in performing principal duties and responsibilities as research projects evolve.
Required Qualifications:
Bachelor's degree in Biology, Biochemistry, Life Science, Engineering, Physiology or a related scientific field required.
0-1 years related work experience required.
Familiarity with basic laboratory instruments and equipment, computers (databases, spreadsheets, statistics) and scientific procedures.
Basic familiarity with computers. Ability to navigate at a basic level within web-based applications.
Competencies:
Decision Making:Ability to make decisions that are based on specific instructions, standard practices and established procedures which generally require little or no supervision.
Problem Solving:Ability to address problems that are routine, somewhat repetitive and generally solved by following clear directions and procedures and by identifying opportunities for process improvements.
Independence of Action:Ability to follow general instructions and procedures as provided. Work is monitored by supervisor/manager.
Written Communications:Ability to communicate clearly and effectively in written English with internal and external customers.
Oral Communications:Ability to understand spoken English in order to follow basic safety instructions and take direction from supervisors; communicate effectively in basic English with patients, families and medical center staff in response to routine questions.
Knowledge:Ability to demonstrate basic knowledge of fundamental concepts, practices and procedures with the ability to use them in routine situations. Specialized knowledge not required.
Team Work:Ability to interact respectfully with other employees, professional staff and/or external contacts to offer ideas, identify issues, obtain information or deliver services.
Customer Service:Ability to demonstrate a positive attitude and respond to requests in a timely and respectful manner.
Physical Nature of the Job:Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move through out the hospital campus
