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Req #: 211011 Department: ALLERGY AND INFECTIOUS DISEASES Posting Date: 08/09/2022 Closing Info: Open Until Filled Salary: Salary and benefits are competitive. Salary is commensurate with qualifications and experience. Shift: First Shift Notes: As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here. (https://hr.uw.edu/benefits/wp-content/uploads/sites/3/2018/02/benefits-professional-staff-librarians-academi-staff-20210208.pdf) As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world. UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. The Department of Medicine: Allergy and Infectious Diseases has an outstanding opportunity for Research Scientist/Engineer 4 - CERID to join their team. Field of Research: The overall goal of the research is to discover new drugs for the treatment of these infectious diseases and cancer. Work will be done in collaboration with the UW Chemistry Department or WuXi Inc. who will supply the novel compounds to test for inhibition of parasite enzyme. Purpose of Research: Perform and guide laboratory research work in support of studies on infectious disease pathogens in both human and animals. Perform and guide laboratory research work in support of studies on prostate cancer. Work as a team of researchers on novel drug candidates in the difficult process to find and develop treatments that for pathogens in both human and animals. Work as a team to develop a treatment for prostate cancer. Stakeholders: NIH funded Project Grants administered in the UW Department of Medicine, Division of Allergy and Infectious Disease, CERID. DUTIES AND RESPONSIBILITIES Coordinate and participate in all aspects of new drug discovery pipeline in the wet lab. 25% Perform specialized small animal studies in mice/rats to test efficacy of compounds. 25% Perform screening of compound libraries for new lead test articles to investigate for treatments. 15% Participate in weekly/monthly programmatic meetings. 15% Design SOPs, establish lab duties, and assign these duties to other lab members. 10% Troubleshoot experimental and equipment problems. 5% Participate in special focus meetings and conferences as requested as well as write manuscripts for scientific publications and conferences. 5% Supervisory Responsibilities: Supervisor at least 1.0 FTE Research Scientist and student workers within University of Washington Van Voorhis laboratory at CERID, SLU. MINIMUM REQUIREMENTS Master's Degree in Molecular Biology or related field and at least 4 years of experience. Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration. ADDITIONAL REQUIREMENTS Mentor or leadership skills/experience. Knowledgeable in molecular biology techniques such as DNA isolation, thermal melts, and library screenings. Experience in development of biochemical enzyme assays. Good organizational skills and the ability to lead a team of researchers and student assistants. Sterility and tissue culture techniques needed to perform cytotoxicity assays and parasite inhibition assays. DESIRED QUALIFICATIONS Experience working with infectious pathogens in BSL-2 conditions including culture of cell lines and organisms as well as performing drug screening assays. Experience with murine models of Cryptosporidium. Maintain daily cultures of organisms. They will test compounds for activity against the organisms in both in vitro and animal models. They will perform in vitro assays of possible drug compounds and compound libraries. Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed. University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.
