Apex Systems is actively hiring for a Staff Research Associate II with a major Experimental Laboratory in the San Francisco, CA area!
For immediate consideration, please send your most up-to-date resume in a Word Document to: Tyniesha at
Job Type: Full-time; Contract to Hire
Job Summary: We are hiring a Staff Research Associate II (SRA II) to work as part of a research team investigating mechanisms of immunity to Mycobacterium tuberculosis, especially myeloid cell differentiation and trafficking, and antigen-specific T cell responses in tissues. The successful candidate must show documented proficiency in BSL2 and BSL3 biosafety, rodent handling and tissue harvest techniques, aseptic technique, and cellular and molecular immunology techniques including primary cell isolation, flow cytometry, and functional cell assays, as well as recombinant DNA technologies. Duties will include standard and repetitive technical laboratory procedures.
The job will involve the ability to stand and walk for extended period during the work hours which is necessary to perform lab duties.
We're about creating exceptional experience for our employees. Our goal is to provide opportunities for our diverse employee population to develop and grow careers in a team-oriented environment focused on research.
Be involved in the ordering of lab supplies and reagents.
Be involved in BSL3 upkeep and inventory management
Receive and create inventories for lab items.
Provide oversight for specimen storage and tracking systems.
Coordinate meeting room set up as needed
Maintain mice colony and database
Ship and receive biohazard agents.
Assist other lab members, including graduate students, postdoctoral fellows, and senior researchers with projects involving infection of mice with Mycobacterium tuberculosis and subsequent analyses of myeloid cell differentiation and trafficking and antigen-specific T cell responses in tissues.
Construct and verify plasmids for targeted bacterial gene deletion and/or recombinant gene expression.
Take primary responsibility for routine isolation of mouse bone marrow cells and preparation of bone marrow stem cell-derived macrophages and dendritic cells.
Take primary responsibility for isolation and differentiation of T cell antigen receptor transgenic T cells, for use in in vitro and in vivo assays.
Take primary responsibility for expression and purification of recombinant proteins and for purification and labeling of antibodies.
Attend and present research data in lab meeting, departmental and institutional meetings as necessary
Required Position Qualifications/Education:
BA/BS degree in a related science and one or more years of recent, directly related work experience, utilizing the techniques or methods required by the position; and/or an equivalent experience/ training.
Molecular biology, Microbiology and / or Immunology research or laboratory background
Knowledge of various procedures and laboratory techniques, such as: BSL2 / BSL3 biosafety experience, rodent research techniques (euthanasia, tissue harvest, injections, genotyping and phenotyping), microscopy, sterile procedure, cell culture, immunology techniques (flow cytometry / FACS, ELISA), recombinant DNA techniques, reagent preparation, protein analysis by immunoblot, RNA isolation and qRT-PCR
Proficiency in various computer programs and proven ability to quickly learn and optimize new programs
Experience in shipping and handling of biohazard agents
Must be open to working in ABSL3 setting
Ability to adapt and use good judgment when making decisions
Ability to work with, and train staff of wide range of educational backgrounds
Ability to prioritize work and delegate responsibility and tasks appropriately
Minimum two years' post-graduation laboratory research experience in microbiology and / or immunology
Experience in biocontainment (Biosafety Level 3) facility
Certification in rodent handling
Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or