Employee Responsibilities:Provide analytical chemistry support to projects across the clinical drug development pipelineExecute test method protocols for in-vitro biopharmaceutics team that includes but not limited to thermodynamic solubility measurement, USP dissolution, precipitation and flux assaysPrepare analytical solutions and biorelevant media for in-vitro experiments, including accurate weighing, potency corrections, buffer preparation, and appropriate handling of active pharmaceutical ingredientsAnalyze study samples by HPLC and UV-vis, including calibration standard preparation, sample processing, and quantitation of drug concentration from in-vitro studiesPerform first-pass review of dissolution, solubility, and analytical data, identifying anomalous results (e.g., carryover, precipitation, coning, filtration loss) for scientific follow-upDocument findings in electronic lab notebooks and technical reports in accordance with ALCOA data integrity principlesSupport routine laboratory operations, including equipment readiness, consumables, safe lab practices, and scheduling instrumentsAdapt experimental execution and prioritization to shifting project needs, balancing scientific rigor with resource efficiency and study objectives
