At ICON, it’s our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients’ lives.Our ‘Own It’ culture is driven by four key values that bring us together as individuals and set us apart as an organisation: Accountability & Delivery, Collaboration, Partnership and Integrity. We want to be the Clinical Research Organisation that delivers excellence to our clients and to patients at every touch-point. In short, to be the partner of choice in drug development.That’s our vision. We’re driven by it. And we need talented people who share it.If you’re as driven as we are, join us. You’ll be working in a dynamic and supportive environment, with some of the brightest and the friendliest people in the sector, and you’ll be helping shape an industry.The RoleWe are seeking a Research Tech IV-(HMAP) to join a dynamic and growing team at the Walter Reed Army Institute of Research (WRAIR) Wound Infection Department (WID). WID is tasked with delivering specific, effective countermeasures for infection of combat wounds pre-injury, at the point-of-injury, and post-injury. The Human Monoclonal Antibody Platform (HMAP) group focuses on in vitro and in vivo research of virulence factors associated with ESKAPEE pathogens and developing monoclonal antibodies against them.What You Will Be Doing-But are not limited to:
Perform a variety of laboratory procedures and be familiar with the field's concepts, practices and procedures including, but not limited to, microbiology, immunology and molecular biology.
Work as part of a scientific team to understand and resolve complex biological questions while contributing to product development through the analysis and interpretation of data and presentation of findings at meetings.
Serve as a technical expert in microbial pathogenesis, microbial genetics, genomics and related virulence factors in one or more of the ESKAPEE pathogens ( Enterococcus species, Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , Enterobacter cloacae , and Escherichia coli ) (a minimum of five studies or as required)
Perform research on monoclonal antibody development for microbial pathogens of military relevance and animal testing
Develop and recommend research protocols and experimental techniques on monoclonal antibody development for submission and approval by the department chief (a minimum of five studies or as required) and report to the COR annually.
Conduct research on projects associated with virulence factors and monoclonal antibody development for one or more of the ESKAPEE pathogens ( Enterococcus species, Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , Enterobacter cloacae , and Escherichia coli ) (a minimum of five studies or as required).
Plan, coordinate and perform microbiological studies on virulence factors and monoclonal antibody development, to include animal modeling, under biosafety level two (a minimum of five studies or as required).
Express and purify recombinant proteins for antibody production, deliver antibodies, crystallize antigen: antibody complexes and mass spectrometry of all products.
Keep accurate and complete records of research done in accordance with applicable standards.
Submit reports and data summaries as requested and prepare research results for presentation and publication in the scientific literature.
Provide all job-related progress reports/technical reports as requested.
Maintain laboratory operation to include insuring stocks of laboratory supplies and reagents, ordering supplies and preparing supply requests for approval, annual inventory of micro-organisms, annually updating of technical research support area SOPs, maintaining a supply of clean glassware, properly disposing of hazardous biological and chemical waste, preparing reagents, and maintaining an inventory of laboratory chemicals, orderliness and cleanliness.
Maintain a safe workplace ensuring that he/she is aware of and observes appropriate safety and occupational health rules and regulations.
Comply with occupational health and safety standards and complete all required safety, biosafety and security training classes as established by WRAIR as minimal standard in the Joint Safety Manual.
Your Profile:
Citizenship: Must be a US citizen.
Clearance: Ability to obtain NACI.
Education: Bachelor of Science in Microbiology, Immunology, Molecular Biology and Biochemistry or similar disciplineYears’ Experience: At least three (3) years of experience in a scientific laboratory setting
Experience with small animal models (Required)
Experience with antibody development is (Required)
Proficiency in basic laboratory techniques and mathematics skills (Required)
Must have ability to perform work at a high level of accuracy and maintain detailed records of research.
Strong computer skills and experience with relevant software including MS Office and GraphPad Prism.
Interpersonal Skills: Strong communication, problem-solving, teamwork, attention to detail, reliability, and multitasking abilities.
Additional Information:Onsite at Walter Reed Army Institute of Research in Silver Spring, MD
Must obtain required occupational physical examinations, annual serological tests and any required security clearance to conduct work in department laboratories.
Night and weekend hours may be required
Benefits of Working in ICON:Our success depends on the quality of our people. That’s why we’ve made it a priority to build a culture that rewards high performance and nurtures talent.We offer very competitive salary packages. And to keep them competitive, we regularly benchmark them against our competitors. Our annual bonuses reflect delivery of performance goals – both ours and yours.We also provide a range of health-related benefits to employees and their families and offer competitive retirement plans – and related benefits such as life assurance – so you can save and plan with confidence for the years ahead.But beyond the competitive salaries and comprehensive benefits, you’ll benefit from an environment where you are encouraged to fulfil your sense of purpose and drive lasting change.ICON is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.#LI-TG2#LI-ONSITE
