Research Instructor PositionDepartment of Pharmacology and Chemical BiologyUniversity of Pittsburgh School of MedicineA Research Instructor position in the Department of Pharmacology and Chemical Biology and the UPMC Hillman Cancer Center is immediately available in the laboratory of Dr. Van Houten at the University of Pittsburgh. The funded project will focus on the interaction of DNA repair proteins at sites of damage through biochemistry, single-molecule techniques, and cell biology. The lab's current projects focus on mechanistic studies of nucleotide excision repair and base excision repair protein interactions with damaged nucleotides in DNA and chromatin. We are particularly interested in developing novel therapies and biomarkers for the treatment of cancer through monitoring or altering DNA repair capacity.Necessary research skills include advanced molecular and cellular biology techniques. Some experience or knowledge of single-molecule techniques is desirable. Prior experience involving the use of DNA manipulation, structure-function studies, and enzyme assays would be ideal. In addition, candidates should have outstanding critical thinking and problem-solving skills and excellent written and oral skills. Salary is commensurate with experience. Applications from women and minorities are strongly encouraged.To apply for the position, qualified candidates with a PhD degree in genetics, biochemistry, cell biology, physiology, or pharmacology, should complete an application in the Talent Center at https://www.join.pitt.edu/#24001378.Please forward a description of technical skills and 2-3 reference letters.The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community. This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover, belong, contribute, and grow, while honoring the experiences, perspectives, and unique identities of all.The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets.PI238514938
