As a member of the Late-Stage LNP Process Development team, the candidate will be joining a team conducting laboratory studies to support the process development, process scale-up, and process characterization of LNP clinical stage drug products. The successful candidate will have experience with LNP process development (having additional experience in tech transfer and GMP manufacturing is a plus but not required), and a desire to contribute to a team focused on establishing science-based manufacturing solutions for complex nucleic acid-based drug products. In this highly collaborative and cross-functional role, the candidate will support the refinement of process control and improve process understanding for multiple programs at various stages of clinical development.Support routine process development and process characterization activities centered around the LNP drug product manufacturing process. Batch ranges vary from 10 mg to 1 gram.Execute routine analytics including dynamic light scattering (DLS), UV-quantification via Ribogreen®, pH, and osmolality for in-process monitoring.Perform experiments under limited to no supervision under subject matter expert guidance.Organize and analyze data, interpret results, and present findings within the process development team and cross-functionally.Author technical documentation (SOPs, reports, protocols) as required.Document experiments and protocols using electronic lab notebooks (e.g., Benchling).Maintain laboratory equipment, order critical reagents, and support operational excellence activities.
