Purification Associate Scientist - HPLC

Purification Associate Scientist - HPLC

24 Oct 2026
Massachusetts, Boston, 02108 Boston USA

Purification Associate Scientist - HPLC

We are seeking a highly motivated HPLC & Purification Associate Scientist to support a client team in synthetic molecule design and development. The candidate will be part of a diverse team of analytical chemists, organic chemists, pharmaceutical scientists, and engineers delivering products and process understanding across a broad range of platforms (e.g. small molecules, peptides, and oligonucleotides). The successful candidate will be a collaborative, detail-oriented scientist with a strong desire to learn, adapt, and contribute to a fast-paced research environment. This role offers the opportunity to work across multiple scientific disciplines while leveraging advanced HPLC, purification, mass spectrometry technologies, and automated laboratory platforms to drive research and development programs.Job Responsibilities:Independently perform mobile phase preparation, column installation, and follow SOP for standard weekly verification of Waters HPLC and tandem Mass Spec systems for walk-up use.Perform robust analytical methods (e.g. HPLC purity, potency) following established SOP protocols.Perform purification using Cytiva Akta systems (Unicorn software) for material generation following written SOP procedures - on the job training is available (background knowledge is preferred).Perform laboratory activities with a strong emphasis on safety and technical rigor, while adhering to local policies and procedures.Support method development under the guidance of an experienced analytical scientistSupport the set-up and operation of a high-throughput liquid handler (Tecan Fluent) to screen reaction conditions and high-throughput chromatographic process development.

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