Work ScheduleStandard (Mon-Fri)Environmental ConditionsAdherence to all Good Manufacturing Practices (GMP) Safety Standards, OfficeJob DescriptionAt Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.Key responsibilities:
Evaluate and develop analytical methods for real-time monitoring of cell therapies using enabling technologies and traditional process analytical technologies
Evaluate and develop on-line, in-line, or at-line analytical methods for process monitoring, in-process analytics, and process characterization
Development of spectroscopic methods (Raman, NIR, FTIR) for process monitoring of biologics such as mAbs, proteins, viral vaccines, or gene therapy vectors. Preferred experience with cell therapy products
Experience with in-line probes, such as capacitance and Raman spectroscope, and development of statistical and regression models using advanced data analytics
Experience developing at-line or online methods using process automation, miniaturization, or high-throughput analytics
Experience in professional capacity developing soft sensors and statistical process models using data science approaches such as ML and AI
Familiarity or experience with robotic liquid handlers such as TECAN or Hamilton and their associated scripting software
Education and Experience:
Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’)
OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
OR PhD
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.Knowledge, Skills and Abilities:
Hands-on experience with evaluating and/or implementing PAT tools for real-time monitoring of bioreactor
Experience using ML such as PCA, PLS, and clustering methods
Experience developing and deploying chemometric models for quantitative analysis of bioreactor status
Proficiency with scripting languages such as Matlab, Python or R and analytical softwares such as JMP, SIMCA, Unscrambler, etc.
Familiarity with data visualization tools such as PowerBI, Spotfire
Understanding of bioprocessing, gene therapy process development, characterization, and manufacturing
Team player, innovative, collaborative, and initiative
Working Environment:Below is listed the working environment/requirements for this role:Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.Able to work upright and stationary and/or standing for typical working hours.Able to lift and move objects up to 25 poundsAble to work in non-traditional work environments.Able to use and learn standard office equipment and technology withproficiency.May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.BenefitsWe offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
