Job DescriptionThermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them.Location/Division Specific InformationWork Location: San Francisco, CA (on-site)Group: Pharma Services GroupDivision: Pharma Services DivisionBusiness Unit: Advanced TherapiesThermo Fisher Scientific has made a significant investment in the dynamic and rapidly growing Cell Therapy space. We recently opened a 44,000-square-foot, brand-new cell therapy collaboration center on the UCSF Mission Bay campus. The facility will serve as a central location where customers and UCSF researchers will have access to Thermo Fisher Scientific’s broad portfolio of solutions and clinical and commercial cGMP cell therapy manufacturing services, along with associated technology development support to UCSF and other partners. In the Cell Therapy group, we focus on providing development and clinical scale services for gene and non-gene modified cell processing for a variety of unmet medical needs.How will you make an impact?With guidance, you will apply technical skills to conduct experiments and studies to support our clients’ cell therapy needs and to assist in meeting the goals of the Cell Therapy group. Your experience and understanding of analytical design and development to establish new analytical methods and standard procedures for cell therapy product characterization will be used for collaborative planning, performing, and troubleshooting experiments, and assisting with other lab activities.What will you do?
Lead process development and optimization activities associated with autologous and allogeneic cell therapy workflows with the aim to improve costs, speed, and quality of the product
Work with blood cells or stem cells and routinely perform cell selection and activation, engineering (viral and non-viral), expansion, and cryopreservation
Design experiments, analyze data and present data to internal and external collaborators or customers
Serve as a process development subject matter expert to tackle technical challenges and support laboratory investigations
Participate in customer core teams as the technical lead for that project
Handle all project-related activities including the availability and suitability of materials and equipment to complete their assignments; coordinating hand-off of samples for downstream process and/or testing; Maintain accurate and detailed laboratory notes
Contribute to the development of closed automated platforms that will be used for cell therapy manufacturing
Work closely with clients for technology transfer activities, and with MS&T and Operations teams to transfer optimized process for clinical manufacturing and play a significant role in to trouble-shooting process challenges.
Plan and implement resolutions to technical problems/issues
Serves as a technical resource for junior staff and apply expertise in laboratory technology as a functional resource/trainer.
How will you get here?Education
BS or MS in biological sciences or engineering field
Equivalent combinations of education, training, and relevant work experience may be considered
Experience
5+ years of relevant cGMP experience in a manufacturing pharmaceutical/biotech environment or related areas
Cell therapy automation technologies, closed system culture vessels, cell washers, cell separation technologies for autologous/allogenic product manipulation
Experience in process development or manufacturing setting is helpful
Aseptic cell culture processing (T cells, NK cells, CAR-T, or Stem Cells) in ISO 5 biosafety cabinets while using universal precautions for handling of human-derived materials preferred
Experience in viral or non-viral genetic modification is helpful
Knowledge, Skills and Abilities
Understanding ‘why’ and not just the ‘how’ of processes and practices
Ability to drive safety, quality, functional, technical and operational excellence
Ability to work within cross functional teams and provide governance on project teams
Cell culture and aseptic techniques
Proven understanding of cGMP practices
Effective written, interpersonal, and presentation skills.
Excellent MS Office skills
Ability to travel up to 20%
Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us (https://jobs.thermofisher.com/global/en/5-reasons-to-work-at-thermo-fisher-scientific) . As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory at Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.Apply today! http://jobs.thermofisher.comThermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.Accessibility/Disability AccessJob Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at 1-855-471-2255. Please include your contact information and specific details about your required accommodation to support you during the job application process.This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response.Compensation and BenefitsThe salary range estimated for this position based in California is $110,000.00–$148,000.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewardsThermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
